78 Results for "

Polygonum capitatum Buch.-Ham. ex D. Don Prodr

" in MedChemExpress (MCE) Product Catalog:
Products (78)

78 Results for "Polygonum capitatum Buch.-Ham. ex D. Don Prodr" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-108357
CAS No.: 157-03-9
Pureté:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; Don
Domaines de recherche:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
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9
9 Cited Publications
Cat. No.: HY-122218
CAS No.: 1998725-11-3
Pureté:  ≥98.0%
Target:  

Glutaminase

Domaines de recherche:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
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7
7 Cited Publications
Cat. No.: HY-N3442
CAS No.: 5041-67-8
Juglanin, a occurring flavonoid that can be isolated from crude Polygonum aviculare, is a JNK acticator, with anti-inflammatory, anti-oxidant and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells .
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1
1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM .
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1
1 Cited Publications
Cat. No.: HY-N11003
CAS No.: 155179-22-9
Vanicoside A is a phenylpropanoid glycoside. Vanicoside A can be isolated from Polygonum pensylvanicum. Vanicoside A inhibits protein kinase C (PKC), induces substantial ROS production. Vanicoside A exhibits anticancer activity against melanoma .
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Cat. No.: HY-N11678
CAS No.: 131180-21-7
Synonyms: Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside
Target:  

Drug Metabolite

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
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Cat. No.: HY-W099547
CAS No.: 2197-63-9
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
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Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Domaines de recherche:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
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Cat. No.: HY-137910
CAS No.: 335104-84-2
Pureté:  98.84%
Domaines de recherche:  

Infection

Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .
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Cat. No.: HY-D0854
CAS No.: 3244-88-0
Synonyms: Acid Violet 19; Acid fuchsin sodium
Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
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Cat. No.: HY-N12348
CAS No.: 928262-58-2
Emoghrelin, isolated from? Heshouwu Polygonum multiflorum, stimulates growth hormone secretion via activation of the ghrelin receptor .
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Cat. No.: HY-N1725
CAS No.: 122872-03-1
2-Desoxy-4-epi-pulchellin (compound 13) is a compound isolated from dichloromethane-soluble portion of Polygonum hydropiper .
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Cat. No.: HY-N3706
CAS No.: 15297-92-4
Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
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Cat. No.: HY-P11097
CAS No.: 3056822-31-9
Target:  

CD47

Domaines de recherche:  

Cardiovascular Disease Cancer

Pep-20 is a CD47 binder with a human Kd of 2.91 µM and a murine Kd of 3.63 µM. Pep-20 blocks the interaction between CD47 and SIRPα, with an IC50 of 24.56 µM for human targets and 12.03 µM for murine targets. Pep-20 also acts as a phagocytosis enhancer and an inducer of anti-tumor immune responses. By blocking the CD47/SIRPα interaction, Pep-20 reduces the tyrosine phosphorylation level of SIRPα, disrupts the inhibitory "don't eat me" signaling pathway, enhances macrophage-mediated phagocytosis of solid tumor cells and hematologic tumor cells, and promotes macrophage mobilization of anti-tumor T-cell responses. Pep-20 can be used in research related to solid tumors, hematologic malignancies, breast cancer, and pancreatic cancer .
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Cat. No.: HY-136504
CAS No.: 434-85-5
Synonyms: Dianthrone
Target:  

Others

Domaines de recherche:  

Others

Bianthrone (Dianthrone) is a natural product that can be isolated from Rheum officinale Baill. Bianthrone is a potential toxic marker of Polygonum multiflorum Thunb .
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Cat. No.: HY-N6685
CAS No.: 50722-38-8
Synonyms: 3-AcDon; 3-ADon
3-Acetyldeoxynivalenol (3-AcDON; 3ADON), a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a brain-penetrant Fusarium mycotoxin. 3-Acetyldeoxynivalenol induces mRNA expression and production of inflammatory chemokine IL-8 in intestinal cells .
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Cat. No.: HY-N11484
CAS No.: 164022-74-6
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .
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Cat. No.: HY-N11066
CAS No.: 349655-29-4
Anhuienside F is a natural product that can be isolated from the root of Anemone vitifolia Buch.-Ham .
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Cat. No.: HY-179120
CAS No.: 3095661-21-2
Target:  

Myosin

Domaines de recherche:  

Infection

ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
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